The 4-6 Arizona Cardinals come into this game off a road win over the Los Angeles Rams. Prior to that the Cardinals had lost four of their previous five games. The Cardinals will be missing starting quarterback Kyler Murray tonight. That leaves journeyman Colt McCoy to face the formidable 49ers defense. McCoy has one start this season, last week’s victory over the Rams.
The 5-4 San Francisco 49ers are an extremely talented team with a record that does not match their abilities. The 49ers feature the league’s #1 ranked defense as well as the #9 offense, yet they are just one game over .500. San Francisco comes into this game winners of two straight and four of their last six. This talented team, featuring the likes of Deebo Samuel, Christian McCaffrey, George Kittle and Brandon Aiyuk on offense, appears to just now be hitting their stride. That does not bode well for a Cardinals team missing its starting quarterback.
The Cardinals have won three of the last four meetings between these two teams, but I think the 49ers will take this one fairly easily. I have submitted my pick using the widget from our partners at Tallysight. You can follow all my picks throughout the season, as I prove for another season how I’m not made to be a gambler. Seriously, I cannot stress enough how bad an idea it would be to bet real money based on my picks. Don’t do it. Don’t even consider it. Make your own picks, and good luck. And if you do bet, consider using our friends at DraftKings Sportsbook.