Muhammad Wilkerson developed into a star during his final two seasons at Temple. Against questionable competition, he thrived. He had 16.5 sacks and 23.5 tackles for a loss during his final two campaigns at school. When the level of competition is low, I think high production is essential. The jump to the NFL is really high at a smaller school. If a guy cannot dominate his competition, how can he survive in the league. Wilkerson passed that test with the job he did.
He is the typical guy a team could play at end in 3-4 fronts and kick inside in 4-3 looks. At 6'4" and over 300 pounds, he has the right kind of size for a 3-4 end. He has long arms and has shown ability to disengage from blocks against the run. Combine this with good closing speed, and he has the potential to turn into a really good run defender. He also displays good ability to disengage rushing the passer and has an arsenal of moves.
Wilkerson lacks an explosive first step, which causes him to lose leverage at times. He also could stand to get stronger. That will come in an NFL conditioning program. He should be able to add some more bulk to his frame without a problem.
I am not sure Wilkerson will ever be a star in the NFL, but on a team that gives him some time to put on some bulk and develop, he could become a valuable lineman. I would not be doing backflips if he was the pick at 30, but I also would have not have a problem with it.