Here are our picks for this week. At the halfway point, this is anybody's game.
| Game | John B | David Wyatt | Matt Birch | Ryan Alfieri | dvdvil |
| Broncos vs. 49ers | Broncos | Broncos | 49ers | 49ers | Broncos |
| Jaguars at Cowboys | Jaguars | Cowboys | Cowboys | Cowboys | Cowboys |
| Dolphins at Bengals | Dolphins | Dolphins | Dolphins | Dolphins | Bengals |
| Bills at Chiefs | Chiefs | Chiefs | Chiefs | Chiefs | Chiefs |
| Redskins at Lions | Redskins | Lions | Lions | Lions | Lions |
| Panthers at Rams | Rams | Rams | Rams | Rams | Rams |
| Titans at Chargers | Titans | Titans | Chargers | Titans | Titans |
| Vikings at Patriots | Patriots | Patriots | Patriots | Patriots | Patriots |
| Buccaneers at Cardinals | Buccaneers | Buccaneers | Cardinals | Buccaneers | Buccaneers |
| Seahawks at Raiders | Seahawks | Raiders | Raiders | Seahawks | Seahawks |
| Steelers at Saints | Steelers | Steelers | Saints | Steelers | Saints |
| Texans at Colts | Colts | Colts | Colts | Colts | Colts |
| Season Record | "56-42" | "57-41" | "55-43" | "52-46" | "55-43" |