I moved into a first place tie with Wyatt last week, but the big story was dvdvil going 11-2 with his picks to move from a game under .500 to a game out of first place. Here are our Week 5 picks.
| Gane | John B | David Wyatt | Matt Birch | Ryan Alfieri | dvdvil |
| Jaguars at Bills | Jaguars | Jaguars | Bills | Bills | Jaguars |
| Giants at Texans | Texans | Texans | Texans | Texans | Texans |
| Chiefs at Colts | Colts | Colts | Colts | Chiefs | Colts |
| Buccaneers at Bengals | Bengals | Buccaneers | Bengals | Bengals | Bengals |
| Packers at Redskins | Packers | Packers | Packers | Packers | Packers |
| Rams at Lions | Rams | Lions | Lions | Lions | Rams |
| Bears at Panthers | Bears | Bears | Bears | Panthers | Panthers |
| Falcons at Browns | Falcons | Falcons | Falcons | Falcons | Falcons |
| Broncos at Ravens | Ravens | Ravens | Ravens | Ravens | Ravens |
| Saints at Cardinals | Saints | Saints | Saints | Saints | Saints |
| Titans at Cowboys | Titans | Cowboys | Cowboys | Cowboys | Cowboys |
| Chargers at Raiders | Chargers | Chargers | Chargers | Chargers | Chargers |
| Eagles at 49ers | 49ers | Eagles | 49ers | Eagles | Eagles |
| Season to Date | "34-24" | "34-24" | "32-26" | "30-28" | "33-25" |